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Endogenous theta stimulation during meditation predicts reduced opioid dosing following treatment with Mindfulness-Oriented Recovery Enhancement
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- 자료유형학술지논문
- 저자명Hudak, J., Hanley, A. W., Marchand, W. R., Nakamura, Y., Yabko, B., & Garland, E. L.
- 학회/출판사/기관명Nature Publishing Group
- 출판년도2021
- 언어영어
- 학술지명/학위논문주기Neuropsychopharmacology
- 발행사항46(4), 836-843.
- ISBN/ISSN0893133X, 1470634X
- 소개/요약Veterans are more likely to experience pain than the general population [1], with 29% of Veterans reporting chronic pain [2]. Between 2010 and 2016, 25% of Veterans with chronic pain received an opioid prescription [1, 3]. Among its risks, long-term opioid therapy (LTOT) at high doses is theorized to induce maladaptive neuroplasticity in prefrontal, limbic, and striatal circuitry, reducing self-regulatory capacity and promoting opioid dose escalation as a means of preserving hedonic equilibrium [4, 5]. To mitigate opioid-related harms, the Department of Veterans Affairs (VA) launched Opioid Safety Initiatives to decrease opioid prescribing and improve safety monitoring. In response to these initiatives, use of complementary and integrative therapies like mindfulness-based interventions (MBIs) has significantly increased across the VA healthcare system [3].
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