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Mindfulness Is Associated With Treatment Response From Nonpharmacologic Exercise Interventions in Knee Osteoarthritis
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- 자료유형학술지논문
- 저자명Lee, Augustine C.,Harvey, William F.,Price, Lori Lyn,Han, Xingyi,Driban, Jeffrey B.,Wong, John B.,Chung, Mei,McAlindon, Timothy E.,Wang, Chenchen
- 학회/출판사/기관명Elsevier Science B.V., Amsterdam
- 출판년도2017
- 언어영어
- 학술지명/학위논문주기Archives of physical medicine and rehabilitation
- 발행사항Vol.98No.11[2017]_x000D_
- ISBN/ISSN0003-9993
- 소개/요약Objective: To examine the association between baseline mindfulness and response from exercise interventions in knee osteoarthritis (OA). Design: Cohort Study; Responder analysis of a clinical trial subset SETTING: Urban tertiary care academic hospital PARTICIPANTS: 86 participants with symptomatic, radiographic knee OA (mean age, 60 years; 74% female; 48% white) INTERVENTIONS: 12 weeks (twice per week) of Tai Chi or Physical Therapy exercise MAIN OUTCOME MEASURE(S): Treatment response was defined using Osteoarthritis Research Society International criteria indicating meaningful improvements in the Western Ontario and McMaster Osteoarthritis Index (WOMAC) pain, function, or Patient Global Assessment scores. At baseline, participants completed the Five Facet Mindfulness Questionnaire (FFMQ; mean total score ±SD: 142±17) and were grouped into three categories of total mindfulness: higher, medium, or lower. Relative risk (RR) ratios were used to compare treatment response across groups. Results: Participants with higher total mindfulness appeared to be 38% (95% CI: 1.05, 1.83) more likely to meet responder criteria than those with lower mindfulness. We found no significant difference between medium and lower mindfulness groups (RR=1.0; 95% CI: 0.69, 1.44). Among the 5 mindfulness facets, medium Acting-with-Awareness was 46% (95% CI: 1.09, 1.96) more likely to respond than lower Acting-with-Awareness, and higher Acting-with-Awareness was 34% more likely to respond, but this did not reach significance (95% CI: 0.97, 1.86). Conclusions: In this study, higher mindfulness, primarily driven by its Acting-with-Awareness facet, was significantly associated with a greater likelihood of response to non-pharmacological exercise interventions in knee OA. This suggests that mindfulness-cultivat
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