명상도서관

명상도서관

Differential Reduction of IP-10 and C-Reactive Protein via Aerobic Exercise or Mindfulness-Based Stress-Reduction Training in a Large Randomized Controlled Trial 자세히보기
  • 자료유형학술지논문
  • 저자명Meyer, Jacob D.,Hayney, Mary S.,Coe, Christopher L.,Ninos, Cameron L.,Barrett, Bruce P.
  • 학회/출판사/기관명HUMAN KINETICS PUBLISHERS
  • 출판년도2019
  • 언어영어
  • 학술지명/학위논문주기Journal of sport & exercise psychology
  • 발행사항Vol.41No.2[2019]_x000D_
  • ISBN/ISSN0895-2779
  • 소개/요약Exercise and meditation improve health and well-being, potentially through decreasing systemic inflammation. In this study, healthy adults (N = 413) were randomized to 8 weeks of training in aerobic exercise, matched mindfulness-based stress reduction, or wait-list control. Three inflammation-related biomarkers (C-reactive protein, interleukin-6, and interferon-gamma-inducible protein-10) were assessed preintervention, directly postintervention, and 17 weeks later. Within-group analyses found that exercise participants had decreased serum interferon-gamma-inducible protein-10 postintervention and 17 weeks later, whereas C-reactive protein was lower in mindfulness-based stress-reduction participants 17 weeks postintervention only. Self-reported physical activity or amount of meditation practice did not predict biomarker changes. This study suggests that (a) training in aerobic exercise can lower interferon-gamma-inducible protein-10, a chemokine associated with interferon activity and illness, and (b) training in mindfulness meditation may have a delayed effect on C-reactive protein, an important inflammatory biomarker. The findings highlight the likelihood of multiple, distinct pathways underlying the health-promoting effects of these lifestyle interventions.