명상도서관
A Preliminary Study: Efficacy of Mindfulness-Based Cognitive Therapy versus Sertraline as First-line Treatments for Major Depressive Disorder
자세히보기

- 자료유형학술지논문
- 저자명Eisendrath, S. J.,Gillung, E.,Delucchi, K.,Mathalon, D. H.,Yang, T. T.,Satre, D. D.,Rosser, R.,Sipe, W. E.,Wolkowitz, O. M.
- 학회/출판사/기관명Springer Science and Business Media
- 출판년도2015
- 언어영어
- 학술지명/학위논문주기Mindfulness
- 발행사항Vol.6No.3[2015]_x000D_
- ISBN/ISSN1868-8527
- 소개/요약Major depressive disorder (MDD) is the leading cause of disability in the developed world, yet broadly effective treatments remain elusive. The primary aim of this pilot study was to investigate the efficacy of mindfulness-based cognitive therapy (MBCT) monotherapy, compared to sertraline monotherapy, for patients with acute MDD. This open-label, nonrandomized controlled trial examined a MBCT cohort (N = 23) recruited to match the gender, age, and depression severity of a depressed control group (N = 20) that completed 8 weeks of monotherapy with the antidepressant sertraline. The 17-item clinician-rated Hamilton Depression Severity Rating Scale (HAMD-17) was the primary outcome measure of depression to assess overall change after 8 weeks and rates of response and remission. The 16-item Quick Inventory of Depressive Symptomatology-Self Report (QIDS-SR16) was the secondary outcome measure to further assess depression severity. Both cohorts were demographically similar and showed significant improvement in depression ratings. No difference was found in the degree of change in HAMD-17 scores (t(34) = 1.42, p = 0.165) between groups. Secondary analysis showed statistically significant differences in mean scores of the QIDS-SR16 (t(32) = 4.39, p
TOP